Journal: Molecular Cancer
Article Title: Mechanisms of tumor-derived extracellular vesicle-mediated immunometabolic reprogramming and immunotherapeutic resistance
doi: 10.1186/s12943-025-02556-8
Figure Lengend Snippet: Integration of liquid biopsy and artificial intelligence for precision oncology Current and emerging applications of artificial intelligence (AI)-integrated exosome analysis in oncology. At present, exosomes isolated from various body fluids are profiled for molecular contents (nucleic acids, proteins, lipids), which are analyzed via AI algorithms to enable biomarker discovery, early cancer detection, and optimization of exosome-based therapeutics Future directions include the development of multimodal AI systems integrating exosomal multi-omics with clinical and imaging data to support intelligent diagnostic and prognostic platforms. AI-driven microfluidic devices will facilitate real-time exosome monitoring and standardized, large-scale analyses, ultimately advancing precision medicine
Article Snippet: Construction of Microfluidic Exosome Chip for Diagnosis of Lung Metastasis of Osteosarcoma , Completed , Osteosarcoma, lung metastases/Diagnosis and Prognosis , Enrollment number: 60 The association of disease recurrence with plasma levels of exosome and their subgroups , Start: 2020.10.1 Completion: 2022.9.30 , NCT05101655.
Techniques: Isolation, Biomarker Discovery, Imaging, Diagnostic Assay, Clinical Proteomics